Firefighters battled a raging 2-alarm blaze at 887 Park St. in Hartford early Wednesday.
Flames were spotted shooting from the top floor of the four-story building just after 4 a.m.
The building was evacuated and no one was injured, according to fire officials.
The building houses Santiago Market on the bottom floor and apartments on the three floors above the market.
Buses were brought in as a temporary shelter for residents.
Several roads around the building were closed while firefighters worked to bring the flames under control.