Manchester police responded to a Walgreens Pharmacy at 49 Deming St. after an employee called in to report an armed robbery.
Police received the call just before 10 a.m. on Sunday morning.
When officers arrived, an employee told them that a man had entered the store with a weapon.
According to police, the suspect approached the pharmacy counter and pulled out a black handgun and robbed the pharmacy of oxycodone.
The suspect fled the scene. Police are searching for him now. He is described as a possibly clean shaven man in his 30's or 40's, wearing a dark blue hooded sweat shirt, long cargo style shirts with brown or black shoes. He was also wearing aviator style sunglasses, police said.
Anyone with information is asked to contact Manchester Police at 860-645-5510.