Interstate 384 West has reopened after being closed between exits 5 and 4 in Bolton because of icy road conditions in the area of Bolton Notch.
Several spin-outs and crashes were reported earlier.
The state Department of Transportation responded to sand the roads.
This is one of several incidents on the roads on Monday morning, and a special weather statement was issued because of road conditions.
Emergency crews also responded to a crash involving a school bus and a car in the area of 642 Broadview Terrace, Hartford.
No injuries were reported in that crash.