Daniel Hamilton scored all 12 of his points in the second half and UConn closed the regular season Sunday with a 67-46 win over UCF.
Sterling Gibbs added 10 points for the Huskies (21-10, 11-7 American Athletic), who needed the victory to stay in contention for an at-large bid to the NCAA Tournament.
UConn led by just six points at halftime before outscoring UCF 37-22 in the second half.
Tacko Fall had 13 points in just 23 minutes to lead the Knights (12-17, 6-12), who have lost eight of their last nine games.
The 7-foot-6 freshman hit six of his seven shots. The rest of the Knights were 10 of 39 from the floor.
UConn will enter next week's conference tournament as the fifth seed. UCF will be seeded seventh.