Saniya Chong, making her first start in more than a year, scored 18 points to lead top-ranked UConn to its 49th consecutive win with a 95-35 rout of Tulsa on Wednesday night.
Morgan Tuck scored 16 of her 18 points in the first half and the three-time defending national champions (12-0, 2-0 American) had five players in double figures.
Freshman Katie Lou Samuelson had 14 points while Breanna Stewart added 12 points and nine rebounds.
Tuck hit her first four shots from the floor and UConn held Tulsa without a basket for the final five minutes of the first quarter, part of a 15-0 run that put the game away early. A jumper by Stewart put the Huskies up 49-18 at the half.
Ashley Clark had 10 points for Tulsa (5-9, 2-1), which was coming off a pair of two-point wins to open its conference season.
Chong started in place of point guard Moriah Jefferson, who pulled her right hamstring in practice Friday and missed her first game after 90 consecutive starts.
Jefferson, who participated in pregame drills, is averaging 13.2 points and 6.1 assists. She had played in all 129 previous games during her UConn career, leading the Huskies to 124 wins.
She wasn't needed in this one.
Chong hadn't started since the team's last loss which came against Stanford in November 2014. She made six of her 11 shots and had four rebounds and four assists.
Despite relying mostly on their bench, the Huskies outscored Tulsa 24-7 in the third quarter and cruised through the rest of the game.
UConn dominated the undersized Golden Hurricane in the post, outscoring Tulsa 42-18 in the paint.
They also scored 33 points off 19 Tulsa turnovers, outrebounded the Hurricane 52-29 and blocked 10 shots.
The Hurricane starting lineup included just one player, 6-foot-2 center Crystal Polk, who is taller than 5-11. UConn had just one starter, the 5-8 Chong, who is under 6-feet tall.
The Huskies shot 50.7 percent from the floor and held Tulsa to just 26.7 percent.
This was just the third meeting between the two programs. UConn won last year's games by 38 and 46 points.
The Huskies have never lost an American Athletic Conference game. They have now won all 38 regular-season contests in addition to their six AAC Tournament games.
The 49-game winning streak is the third longest in program history, behind their NCAA record 90-game streak from 2008-10 and a 70-game streak in 2001-03.
Tulsa: The loss snapped a two-game winning streak for the Hurricane, who won their first two conference games for the first time since 2007-08, when they were members of Conference USA.
UConn: Stewart's nine rebounds give her 945 for her career and moved her past Peggy Walsh (937) into sixth place on UConn's career rebounding list. Tina Charles tops that list with 1,367.
UConn: The Huskies begin a three-game road trip on Friday at Houston.
Tulsa: The Hurricanes continue their three-game road trip on Friday at Temple