Two cars collided on Starkweather Road in Plainfield, sending three people to the hospital on Monday.
The cars hit head-on around 12:30 p.m., according to police.
The driver of one car, Stephanie Januszewski, 29, of Salem, was seriously injured and taken to Backus Hospital in Norwich before being flown by Life Star to Hartford Hospital.
The second car was being driven by 76-year-old Marcia Huhta, of Moosup. She was flown by Life Star to Rhode Island Hospital. Her passenger, 76-year-old Matti Huhta, was taken to Rhode Island Hospital with minor injuries, police said.
Police are investigating the cause of the accident.