The Berlin Turnpike was shutdown between Middletown Road and Worthington Ridge because of an accident involving a wrong-way driver early Saturday morning.
Berlin Police said a wrong-way driver was heading north in the southbound lanes of the Berlin Turnpike and collided with another vehicle.
Three people were transported to Hartford Hospital with serious injuries.
The road was reopened a few hours later.
Police are asking anybody who may have witnessed the crash to call 860-828-7080.
