Emergency crews responded to Ragged Mountain in Berlin after getting a report of an injured hiker on Saturday.
A hiker reportedly suffered an ankle injury on a portion of the New England Trail, fire officials said.
Responding crews hiked in and contacted the injured hiker in what they described to be a remote location of the preserve about 45 minutes after the time of the call.
A second crew came from a different area of the mountain and ultimately transported the injured hiker to a nearby hospital for further evaluation and treatment.
Fire officials said it happened around 2 p.m.