Guilford police are investigating a serious crash near Route 77 and the I-95 exit ramp.
Police said two cars crashed and people in both vehicles were hurt. The extent of the injuries and number of people involved were not immediately clear.
The road is closed in the area. Drivers should seek alternate routes.
Anyone who witnessed the crash is asked to contact the Guilford Police Department at 203-453-8061.
No other details were immediately available.