Ke'Mon Freeman and Xavier Jones each ran for more than 100 yards and combined for five touchdowns as SMU climbed within a win of bowl eligibility by outscoring UConn 62-50 on Saturday.
Ben Hicks threw for 276 yards and a score for the Mustangs (5-5, 4-2 American), who are at .500 for the first time this season.
UConn quarterback David Pindell threw for 215 yards and four touchdowns ran for 181 yards and two others. He becomes first Husky quarterback to ever to rush for 1,000 in a season and the first UConn player to do it since tailback Lyle McCombs in 2011.
Kevin Mensah ran the ball 28 times for 184 yards and a score for UConn (1-9, 0-6).
The teams combined for 1,174 yards of offense, 680 on the ground.
SMU's first five drives ended in scores and the Mustangs led 31-10 at the half.
Freeman (116 yards) had first-quarter touchdown runs of 39 and 5 yards and added a 3-yard score in the fourth quarter. Jones (133 yards) had second-half touchdown runs of 52 and 43 yards.
UConn, which has given up more than 50 points six times this season, hasn't beaten an FBS team since October of last year.
SMU: The Mustangs have won five of their last seven games after starting the season 0-3. SMU put up 594 yards of total offense and 315 yards rushing under coordinator Rhett Lashlee, who coached the UConn offense last season.
UConn: The Huskies had 580 yards of offense, including 365 on the ground. Pindell has eclipsed 100 yards on the ground six times this season, including the Huskies last four... UConn linebacker Eli Thomas, who suffered a stroke a month ago, walked onto the field before the game to participate in the coin toss.
SMU returns home to face Memphis on Friday night.
UConn travels to East Carolina to play a Saturday night game