Drea De Matteo Leaving ‘Desperate Housewives'; Is Dana Delaney Departing Too?

Drea de Matteo is departing Wisteria Lane.

The former "Sopranos" star, who brought her family-on-the-run to "Desperate Housewives" earlier this season, will leave the show in May, Entertainment Weekly's Michael Ausiello first reported.

Series creator Marc Cherry told the columnist that Drea wasn't meant to be a long-running series regular

"Part of the deal when we hired Drea was she was only interested in doing one season," he said. "She has a baby and is eager to get back to her life in New York."

The show creator said before Drea's character, Angie Bolen, is ushered out of the drama, plenty will be revealed.

"As we build toward the end and we start undoing the many layers of [Angie], everyone will get how brilliant she is," he said.

In related "Desperate" news, Dana Delaney may depart the series for "Body of Evidence," an upcoming medical drama on ABC, according to The Hollywood Reporter.

The deal, however, has not yet been made, the trade mag reported.

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