Firefighters have responded to a fire at 149 Maple St. in Naugatuck and fire departments from surrounding towns have been called to provide mutual aid.
Officials believe this was an electrical fire that started on the third floor. No residents were home when fire broke out and no injuries are reported.
Police said several area streets are closed for a couple hours and residents are urged to use alternate routes to avoid detours.
Residents of roads that are closed should be able to get to their homes, in most cases.
Maple Street is closed between South Main and Carroll Streets.
The Route 8 South exit is open, but traffic cannot access Maple Street east of the bridge.
Oak Street is closed between Maple and High streets.
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Carroll Street is closed at Central Avenue and Central Avenue is closed.
Witnesses said pharmacy workers ran out of the building and workers said they evacuated one they smelled smoke.