But as sites ramped up Monday, a bigger focus of testing is becoming clear: health care workers, first responders and those already hospitalized. That’s in part because testing potential cases among the general public may be losing steam as a containment strategy.

The National Museum of American Jewish History in Philadelphia has filed for bankruptcy protection as it seeks relief from debt brought by the museum’s construction efforts to build its 100,000-square-foot location near Independence Mall.

A federal judge entered a final order Tuesday on his ruling last year that a nonprofit’s proposal to open the nation’s first supervised injection site for opioid users in Philadelphia does not violate federal law.

The Supreme Court said Monday it will hear a dispute over a Philadelphia Catholic agency that won’t place foster children with same-sex couples, a big test of religious rights on a more conservative court.

Magic, a 16-year-old American Pit bull Terrier, was buried under a three-story brick wall that fell into his owner’s yard. The family thought he was lost, but the pup wasn’t ready to say goodbye.

Philadelphia Orchestra Music Director Yannick Nézet-Séguin created a playlist to help soothe stressed out shelter animals.

A would-be mother was killed in a shooting Friday night in North Philadelphia that also left a man very seriously wounded, police said. Medical workers performed an emergency cesarean delivery on Ishan Charmidah Rahman, who was six months pregnant, but the baby did not survive, police said. The shooting occurred just before 6 p.m. near North Ninth and West York…

Ari Goldstein, 23, was found guilty of three charges including felony attempted sexual assault of a Temple University freshman inside his bedroom at the Alpha Epsilon Pi fraternity house.

Thousands of pounds of deadly hydrofluoric acid escaped into the atmosphere following the massive June 21 blast at the now-shuttered gas refinery in South Philadelphia, according to a new federal report.

Comcast Spectacor announced plans to build a dedicated competitive gaming arena. The move could help the company capitalize on a growing and lucrative industry.

Kobe Bryant’s retired No. 33 jersey was at last back where it belonged Saturday— unveiled under a spotlight by Bryant’s cousin, his old high school coach, and a former teammate at Bryant Gymnasium in Lower Merion High School.

A father who police say fabricated a story of a robbery and home invasion after his 4-year-old son accidentally shot himself in the head in their North Philadelphia home faces involuntary manslaughter charges.

Police are searching for a man accused of stealing half a million dollars’ worth of jewelry from Philadelphia 76ers legend Allen Iverson.

A massive fire and series of explosions rocked a South Philadelphia refinery complex, the largest on the East Coast, early Friday morning. The blast jolted people from their sleep and prompted a shelter-in-place.

Xavier Johnson sought to rob 64-year-old Renee Gilyard and 20-year-old Jimmy Mao, Philadelphia Police Homicide Capt. Jason Smith said in a news conference Thursday afternoon.

Last May, an air monitor on the border of the East Coast’s largest oil refinery recorded a level of benzene, a cancer-causing gas, more than 21 times the federal limit, NBC News reported.

Drexel University paid the United States nearly $190,000 after a former professor at the school allegedly used federal grant money for visits to Philadelphia strip clubs and sports bars.

At least six people were killed and over 140 people hurt after an Amtrak train, carrying 238 passengers and five crew members, derailed and rolled onto its side in the Port Richmond section of Philadelphia Tuesday night, according to officials.

The city of Philadelphia has agreed to pay $4.15 million to a man who spent 24 years in prison for a murder he didn’t commit, one of the largest such payouts in city history. City officials agreed last week to settle a civil rights lawsuit filed by Shaurn Thomas, who was 20 when he was convicted of second-degree murder in…

The next police commissioner of Philadelphia will be Portland, Oregon, Police Chief Danielle Outlaw. Outlaw, 44, has served as the top-ranking police official for the West Coast city for a little over two years, since October 2017. She was the first black woman to hold the position, according to her biography on the Portland city website. She will also be...